Date/Time: Sunday, March 19, 2023 - 8:45 AM to 10:15 AM
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Abstract(s):

• O-53
  ABLATION OF MONOCYTE CHEMOATTRACTANT
  PROTEIN 1 FROM THE INTESTINAL EPITHELIUM IS
  PROTECTIVE IN THE OA OF OBESITY
  D. Villani1, T. Ishii1, C. X. Mbazoa1, H. Hendesi1, S. H. Landgrave1, K. Payne1,
  A. Gill2, L. Favazzo1, S. Gill2, M. Zuscik1; 1Univ. of Colorado Anschutz Med.
  Campus, Denver, CO, 2Univ. of Rochester Med. Ctr., Rochester, NY
   

  O-54
  EXCESSIVE TRANSFORMING GROWTH FACTOR BETA
  RECEPTOR II SIGNALING DRIVES EARLY AND WORSE
  SPONTANEOUS KNEE OA IN THE ITGA1-NULL MOUSE
  J. St Amant1, J. Michaud1, L. De Guzman1, D. Hinds1, M. Coyle1, J. Trujillo
  Torres1, A. Pozzi2, A. L. Clark1; 1Univ. of Guelph, Guelph, ON, Canada,
  2Vanderbilt Univ. Med. Ctr., Nashville, TN

  O-55
  NOVEL AAV2-FGF18 CHONDROGENIC GENE THERAPY
  A. Goraltchouk1, J. M. Hollander2, F. Luppino1, L. Zeng2, A. Seregin1;
  1Remedium Bio, Inc, Needham, MA, 2Tufts Univ., Boston, MA

  O-56
  PRO-REGENERATIVE IMMUNE CELLS DIRECT
  ARTICULAR CARTILAGE REPAIR IN POST A TRAUMATIC
  OSTEOARTHRITIS MODEL
  J. Bolander1, A. Wilson1, E. Parsons1, C. Clouse1, G. Moviglia1, G. Poehling1,
  T. Herpelinck2, F. Marini1, A. Atala1; 1Wake Forest Sch. of Med., Winston
  Salem, NC, 2KU Leuven, Leuven, Belgium

  O-57
  LINK_TSG6 INHIBITS CARTILAGE DAMAGE IN OA BY
  SUPPRESSING COLLAGENASE AND AGGRECANASE
  ACTIVITY
  S. P. Drummond1, N. Kouvatsos1, J. L. Scott1, L. C. Biant2, S. Anand3, C. M.
  Milner1, A. J. Day1; 1Univ. of Manchester, Manchester, United Kingdom,
  2Manchester Univ. Hosp. Fndn. Trust, Manchester, United Kingdom,
  3Stepping Hill Hosp., Stockport, United Kingdom
   

Speaker(s):

• Michelle Yau, PhD